We aim at elucidating, using bioinformatic methods, how interruptions in cellular regulatory mechanisms contribute to the development of human pathological conditions, primarily cancer.

Gene regulation is a multi-layered process and we mainly study three key tiers of it:

Regulation of gene transcription

Regulation of transcript stability

Regulation of protein translation

Dr. Rani Elkon

Principal Investigator

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Our study of these tiers of gene regulation utilizes various cutting-edge deep-sequencing techniques that allow genomic-scale delineation of regulatory layers that were so far largely unexplored.

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